Sami Hamdoun

26 Publications
2 Departments

Research Publications

2025

Dual targeting of Phosphoinositide 3-Kinase (PI3K) and histone deacetylase 6 (HDAC6) in cancer

Pharmacology & Toxicology Doctor
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2024

Allomaltol derivatives as Antimycobacterial agents: In vitro and in silico evaluations with potential protein targets

Pharmaceutical Chemistry Doctor
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2023

The investigation of drug repurposing for HDAC1 inhibitory effects by in silico and in vitro methods

Pharmaceutical Chemistry Doctor
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2021

1, 2, 3, 4, 6-Pentagalloyl glucose, a RBD-ACE2 binding inhibitor to prevent SARS-CoV-2 infection

Pharmacology & Toxicology Doctor
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2021

Corilagin prevents SARS-CoV-2 infection by targeting RBD-ACE2 binding

Pharmacology & Toxicology Doctor
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2021

Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry

Pharmaceutical Chemistry Doctor
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2020

Synthesis of novel xanthone and acridone carboxamides with potent antiproliferative activities

Pharmaceutical Chemistry Doctor
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2020

SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells

Pharmacology & Toxicology Doctor
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2019

Ca2+ signalling plays a role in celastrol‐mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats

Pharmacology & Toxicology Doctor
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2019

MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate

Pharmacology & Toxicology Doctor
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2019

Biopiracy Versus One-world Medicine–from Colonial Relicts to Global Collaborative Concepts

Pharmaceutical Chemistry Doctor
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2019

Biopiracy versus One-World Medicine–From colonial relicts to global collaborative concepts

Pharmaceutical Chemistry Doctor
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2019

Treatment of subjects with multidrug-resistant cancer

Pharmacology & Toxicology Doctor
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2018

Multifactorial modes of action of arsenic trioxide in cancer cells as analyzed by classical and network pharmacology

Pharmacology & Toxicology Doctor
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2017

Molecular Targeting of Metastatic and Multidrug Resistant Cancers

Pharmacology & Toxicology Doctor
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2017

Ginkgolic acids inhibit migration in breast cancer cells by inhibition of NEMO sumoylation and NF-κB activity

Pharmacology & Toxicology Doctor
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2017

Drug repurposing of the anthelmintic niclosamide to treat multidrug-resistant leukemia

Pharmacology & Toxicology Doctor
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2017

Lawsone derivatives target the Wnt/β-catenin signaling pathway in multidrug-resistant acute lymphoblastic leukemia cells

Pharmacology & Toxicology Doctor
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2017

In silico assessment of the druggability of two novel germacranolides isolated from Capparis decidua (Forsk.) as carbonic anhydrase II inhibitors

Pharmaceutical Chemistry Doctor
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2016

In silico pharmacokinetics and molecular docking of three leads isolated from Tarconanthus camphoratus L

Pharmaceutical Chemistry Doctor
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2016

Biopiracy of natural products and good bioprospecting practice

Pharmaceutical Chemistry Doctor
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2016

Discovery of two diacetylene glycosides as human uridine-cytidine kinase 2 inhibitors: an in silico approach

Pharmaceutical Chemistry Doctor
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2016

Biopiracy of natural products and good bioprospecting practice.

Pharmaceutical Chemistry Doctor
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2016

Cytotoxicity of 91 Kenyan indigenous medicinal plants towards human CCRF-CEM leukemia cells

Pharmacology & Toxicology Doctor
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2016

In silico Pharmacokinetic and Molecular Docking of Three Leads Isolated from Tarconanthus

Pharmaceutical Chemistry Doctor
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2015

Substituted steroidal compounds containing amino and amido groups reverse multidrug resistance of mouse T-lymphoma and two human prostate cancer cell lines in vitro

Pharmacology & Toxicology Doctor
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